E1518 Flavour solvent

E1518 It is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavorings, and for its humectant function, with E number E1518 and Australian approval code A1518. It is used as an excipient in pharmaceutical products, where it is used as a humectant, a plasticizer, and a solvent.

The plasticizing capabilities of E1518 have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel (PTX). In the study, E1518 was combined with PTX, ethanol, a phospholipid, and a medium-chain triglyceride to form a gel-drug complex. This complex was then injected directly into the cancer cells of glioma-bearing mice. The gel slowly degraded and facilitated the sustained release of PTX into the targeted glioma cells.

Additionally, preliminary research also suggests that E1518 can be used to directly treat glioblastoma. The study found that E1518 is a viable mediator for acetate supplementation, a therapy that inhibits glioblastoma cell growth.

E1518 can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and improve the cold and viscosity properties of biodiesel.

It has been considered as a possible source of food energy in artificial food regeneration systems on long space missions. It is believed to be safe to get over half of one's dietary energy from E1518.