E528 Acidity regulator

It is added directly to human food and is affirmed as generally recognized as safe by the FDA.[16] It is known as E number E528.

E528 is marketed for medical use as chewable tablets, as capsules, powder, and as liquid suspensions, sometimes flavored. These products are sold as antacids to neutralize stomach acid and relieve indigestion and heartburn. It also is a laxative to alleviate constipation. As a laxative, the osmotic force of the E528 acts to draw fluids from the body. High doses can lead to diarrhea and can deplete the body's supply of potassium, sometimes leading to muscle cramps.

Some E528 products sold for antacid use (such as Maalox) are formulated to minimize unwanted laxative effects through the inclusion of aluminum hydroxide, which inhibits the contractions of smooth muscle cells in the gastrointestinal tract, thereby counterbalancing the contractions induced by the osmotic effects of the E528.E528 is also a component of antiperspirant.E528 is useful against canker sores (aphthous ulcer) when used topically..